Chiasma, Inc. appointed John Doyle to the position of Senior Vice President and Treasurer of the Company, effective January 19, 2021. On the Effective Date, the Board also appointed Raj Kannan, the Company’s Chief Executive Officer and director, as President of the Company. Mr. Fitzpatrick will continue provide certain consulting services to the Company until June 30, 2021 to assist in the transition of his duties to Mr. Doyle.