BRAIN Biotech : High-performance production strains for enzymes and proteins

For the production of enzymes and proteins by microbial fermentation, BRAIN Biotech's project teams focus on interdisciplinarity: experts from microbiology, molecular biology and bioprocess development work in parallel on strain and bioprocess optimization. An Aspergillus niger strain developed by BRAIN Biotech has proven its suitability as an efficient production strain for enzymes and alternative proteins, with yields in the "double-digit" gram-per-liter range.

Aspergillus as production strain

Case Study: A customer is looking for a microbial strain that produces a specific molecule in the highest possible quantity. How is such a production strain selected? Christian Naumer, Director & Unit Head Bioprocess Development at BRAIN Biotech, explains: "If the customer does not specify a strain, the team decides which microorganism to use after a scientific assessment of the target molecule. Usually, this is a strain that is already recognized as a production strain for the respective application and is classified as safe."