Amarin Corporation plc provided revenue guidance for the year 2016 and 2017. The company estimates full-year 2016 product revenues, on a GAAP basis subject to audit, modestly exceeded $125 million, representing growth of more than 50% over reported 2015 net product revenue of $81 million.  Amarin estimates that changes in channel inventory increased net product revenues by approximately $3 to $6 million during 2016 and that without these increases full-year 2016 net product revenues would have been in the upper end of the company’s previously provided guidance of $112 to $125 million. For the year of 2017, the company estimates U.S. product revenues to reach between $155 and $165 million with quarterly variability continuing based on seasonal factors. Assuming projected revenue growth and spending assumptions, the company expects to be cash flow positive from commercial operations for 2017, excluding REDUCE-IT, interest and royalties.