Advanced Oncotherapy PLC - London-based particle therapy for cancer treatment - Non-Executive Director Michael Bradfield buys 500,000 shares at 13.17 pence, worth GBP65,825, on Thursday. Now has 8.4 million shares, a 1.6% stake.

Current stock price: 13.84p, closed up 4.5% on Friday in London

12-month change: down 63%

By Tom Waite, Alliance News editor

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