Item 5.02 Departure of Directors or Certain Officers; Election of Directors;


          Appointment of Certain Officers; Compensatory Arrangements of Certain
          Officers.



On January 9, 2020, the board of directors (the "Board") of Xenon Pharmaceuticals Inc. (the "Company"), based upon a recommendation from the Nominating and Corporate Governance Committee of the Board, voted to appoint Dr. Clarissa Desjardins as a director of the Company, effective as of January 13, 2020.

There are no transactions and no proposed transactions between Dr. Desjardins (or any member of her immediate family) and the Company (or its subsidiary), and there is no arrangement or understanding between Dr. Desjardins and any other person or entity pursuant to which Dr. Desjardins was appointed as a director of the Company.

Dr. Desjardins will participate in the Company's standard compensation plan for non-employee directors, including an initial stock option grant, which will be granted to Dr. Desjardins on January 13, 2020. The standard compensation plan for non-employee directors is described in the section titled "Director Compensation Policy" of the Company's definitive proxy statement on Schedule 14A, filed with the Securities and Exchange Commission on April 29, 2019.

In addition, on January 8, 2020, Dr. Richard Scheller, submitted his resignation from the Board, effective January 14, 2020. In submitting his resignation, Dr. Scheller did not express any disagreement on any matter relating to the Company's operations, policies or practices.

As a result of Dr. Scheller's resignation and Dr. Desjardins' appointment, Dr. Desjardins was appointed to the Board's Compensation Committee replacing Dr. Scheller effective as of January 13, 2020. Following Dr. Desjardins' appointment to the Board's Compensation Committee, the membership on the three standing committees of the Board is as follows:



                                                        Nominating and Corporate
Audit Committee             Compensation Committee      Governance Committee
Frank Holler (Chair)        Dr. Mohammad Azab (Chair)   Dr. Gary Patou (Chair)
Steven Gannon               Dr. Clarissa Desjardins     Dawn Svoronos
Michael Tarnow              Dr. Gary Patou              Michael Tarnow








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