TScan Therapeutics, Inc. announced its 2023 clinical pipeline plans. Clinical Plans and Expected Milestones: In the hematologic malignancies program, the Company expects to enroll the first two cohorts in the Phase 1 umbrella trial (NCT05473910) for TSC-100 and TSC-101 in the first half of 2023 and to report top-line data by the end of 2023. Additionally, the Company expects to share prevention of relapse data in 2024.

In the solid tumor program, the Company plans to file INDs for HPV (TSC-200-A0201) and PRAME (TSC-203-A0201) in the first half of 2023 with two additional INDs to be filed by the end of 2023; expects preliminary clinical data for the most advanced TCRs by the end of 2023. The company expects to report initial multiplex therapy data for this program in 2024.