Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.



On January 14, 2020, the Compensation Committee of our Board of Directors
approved (i) the annual base salaries for fiscal 2020 for our current principal
executive officer and other executive officers, (ii) target bonus opportunities
for fiscal 2020 (as a percentage of base salary) for our current principal
executive officer and other executive officers, (iii) the payment of various
cash bonuses for the fiscal year ended December 31, 2019 pursuant to our 2019
Incentive Compensation Plan adopted under our Incentive Compensation Plan ("2019
Bonus Plan"), and (iv) the grant of stock options pursuant to our 2014 Equity
Incentive Plan ("2014 Plan"), each as more fully described below:



                                                                                                  2020 Target
                                                                                                     Bonus                                        Shares
                                                       Annual Base           Annual Base          Opportunity             Amounts                 Subject
                                                         Salary                Salary             (as a % of           Earned under              to Stock
Name                                Position          (Fiscal 2019)

(Fiscal 2020)(1) Base Salary) 2019 Bonus Plan Options (3) Evert B. Schimmelpennink Chief Executive


                               Officer, President
                               and Secretary         $       580,000      $         614,800                 60 %     $         435,000               225,000
Shawn Scranton                 Chief Operating
                               Officer               $       300,000      $         350,100                 40 %     $         138,338                55,000
Patrick K. Lucy                Chief Business
                               Officer               $       367,000      $         400,030                 40 %     $         161,847                47,500
Martin Brenner                 Chief Scientific
                               Officer               $       360,000      $         372,960                 40 %     $         125,685 (2)            41,000

(1) Base salary increases are effective as of February 2, 2020.

(2) The cash bonus under the 2019 Bonus Plan for Dr. Brenner is pro rated for his

commencement of employment on March 18, 2019.

(3) The options have a grant date of the first trading day of February 2020. 25%

of the shares subject to the options are scheduled to vest on February 1,

2021, and the remaining shares subject to the options are scheduled to vest

in equal monthly installments thereafter such that all shares shall be fully

vested on February 1, 2024, subject to continued status as a service provider

on each such vesting date.

The option awards described above are subject to the terms and conditions of our 2014 Plan and the applicable forms of agreement, which have been previously filed with the Securities and Exchange Commission.

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