Item 7.01. Regulation FD Disclosure.

On January 10, 2022, Penumbra, Inc. (the "Company" or "Penumbra") announced that, while it is Penumbra's practice not to comment on rumors or market speculation, the Company issued the following statement in response to certain media reports published prior to a large industry conference: "Penumbra is not in discussions with Shockwave Medical to pursue a business combination or similar transaction".

The information in this Item 7.01 is being furnished, not filed, pursuant to Regulation FD. Accordingly, the information in this Item 7.01 will not be incorporated by reference into any registration statement filed by the Company under the Securities Act of 1933, as amended, unless specifically identified therein as being incorporated therein by reference. The furnishing of the information in this Item 7.01 is not intended to, and does not, constitute a determination or admission by the Company that this information is material or complete, or that investors should consider this information before making an investment decision with respect to any security of the Company.

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