N4 Pharma Plc announced that it has appointed the API and Nanomedicines business unit of Ardena as its contract development and manufacturing organization partner for the technology transfer and up scaling manufacture of Nuvec®. The contract is divided into three stages; Establishing an understanding of the current manufacture process, scale-up and analysis of the transfer of technology; Process optimization and scale-up resulting in the manufacture and analysis of a non-GMP 50g batch of Nuvec® and Manufacture, testing and product certification of Nuvec® for GMP status. The manufacture will initially be for the fundamental "naked" Nuvec® silica nanoparticles albeit Ardena has the ability to produce functionalized particles as may be required by the Company or any collaborators from time to time.