MindBio Therapeutics Corp. reported positive secondary data from its world-first take-home microdosing depression trial using MB22001 completed earlier this year. Data from MindBio's Phase 2A Depression trial indicates improvements in a range of secondary outcome measures following an 8-week treatment course with MB22001. This includes a 52% reduction in anxiety (HAM-A), and self-reported reductions in stress (35%), anxiety (59%) and
depression (40%) using the DASS questionnaire. Participant's psychological quality of life was improved by 37% as measured by the WHOQOL. Previously released data reported improvements in MADRS Score (Montgomery-Asberg
Depression Rating Scale) indicating an overall 60% decrease in depressive symptoms at the end of the treatment period and a 53% complete remission from depression. The Company is currently assessing the durability of the antidepressant response of MB22001 at 1 months and 3 months post treatment cycle. The Company looks forward to revealing these highly important antidepressant durability results to the market shortly. Safety analysis has shown a favorable adverse event profile with a low frequency of adverse events with no serious or severe adverse events recorded. No clinically significant abnormalities were seen in follow up blood tests, electrocardiograms or echocardiograms. MindBio has achieved a significant milestone as the only organization in the world that is running multiple clinical trials with Government and Regulatory approvals for take-home use and handling of a psychedelic medicine by trial patients out in the community, specifically a proprietary self-titratable form of Lysergic Acid Diethylamide (LSD) in microdoses designed for take home use (MB22001). The Company is currently dosing in two separate Phase 2B clinical trials, a Depression trial and an Advanced Stage Cancer Trial.