Milestone Scientific Inc. (OTCBB: MLSS), the recognized leader in advanced, computer-controlled drug delivery technologies, will participate in the American Academy of Dental Group Practice (?AADGP?) Conference in Orlando, Florida, from January 26 – 29, 2011, at Booth #104, at the Hilton Hotel in the Walt Disney World Resort.

Joseph D'Agostino, Chief Financial Officer said, ?As much of our sales and marketing efforts have been geared towards group dental practices with the hiring of Marvin Terrell as Domestic Director of Sales, we believe the AADGP presents us a great opportunity to meet with decision makers at these practices. We will have the opportunity to demonstrate how our Single Tooth Anesthesia System (?STA?) can help group dental practices differentiate themselves, increase their efficiency and contribute to their growth and profits. Our dental hygienists will be on hand to educate attendees on the STA system, and show them how it has revolutionized the science of dentistry.?

About Milestone Scientific Inc.

Milestone Scientific is engaged in pioneering advanced computer-controlled drug delivery technologies for the medical and dental markets; and currently sells its award-winning products through a global distribution network serving North America, Central and South America, Asia, Africa and Europe. For more information on the STA Single Tooth Anesthesia System® unit and other innovative Milestone products, please visit the Company's web site found at www.milestonescientific.com or follow the Company on Twitter @painlessdental or become a fan on Facebook at Painless Dentistry.

Safe Harbor Statement

This press release contains forward-looking statements regarding the timing and financial impact of Milestone's ability to implement its business plan, expected revenues and future success. These statements involve a number of risks and uncertainties and are based on assumptions involving judgments with respect to future economic, competitive and market conditions and future business decisions, all of which are difficult or impossible to predict accurately and many of which are beyond Milestone's control. Some of the important factors that could cause actual results to differ materially from those indicated by the forward-looking statements are general economic conditions, failure to achieve expected revenue growth, changes in our operating expenses, adverse patent rulings, FDA or legal developments, competitive pressures, changes in customer and market requirements and standards, and the risk factors detailed from time to time in Milestone's periodic filings with the Securities and Exchange Commission, including without limitation, Milestone's Annual Report for the year ended December 31, 2009. The forward looking-statements in this press release are based upon management's reasonable belief as of the date hereof. Milestone undertakes no obligation to revise or update publicly any forward-looking statements for any reason.

Milestone Scientific Inc.
Joseph D'Agostino, 973-535-2717
Chief Financial Officer
or
Investor Relations:
Porter, LeVay & Rose, Inc.
Linda Decker, 212-564-4700
Vice President