LogicBio Therapeutics, Inc. announced the expansion of the Company's research partnership with Children's Medical Research Institute to develop next-generation adeno-associated virus (AAV) vectors for a range of gene therapy and gene editing applications in the treatment of serious diseases of the liver and two other tissues. New data highlighting the advantages of next-generation AAV capsids developed through the collaboration have been presented at multiple leading scientific conferences including the European Society of Gene and Cell Therapy and the American Society of Gene and Cell Therapy. To design next-generation AAV capsids, the CMRI team applies innovative genetic and molecular biology techniques including bioinformatics, machine learning and other computational methods. CMRI is also developing unique clinically predictive models to select and assess novel capsids. The Company anticipates that expansion of this collaboration will position LogicBio to advance research focusing on areas of unmet need in liver health and in two additional tissues to be announced in the near future. The Company believes that these novel AAV capsids have broad potential applications in gene therapy and for gene editing platforms such as GeneRide™, LogicBio's proprietary gene editing technology that harnesses a cell's natural DNA repair process, known as homologous recombination, to insert a corrective copy of a gene at a precise spot in a patient's genome.