On December 31, 2021, Neil Miotto, a member of the Board of Directors (the “Board”) of GigCapital5, Inc. (the “Company”) and member of the Audit Committee, Compensation Committee, and Nominating and Corporate Governance Committee of the Board, resigned effective immediately. Mr. Miotto's resignation is not the result of any disagreement with the Company. On December 31, 2021, the Board appointed Sharmila Makhija, MD, MBA, as a new member of the Board and as a member of the Audit Committee, Compensation Committee, and Nominating and Corporate Governance Committee of the Board, with such appointment to be effective immediately.

Dr. Makhija has also been appointed to serve as the Chair of the Compensation Committee to be effective immediately. Dr. Makhija fills the vacancy created by the resignation of Mr. Miotto and will serve on the Board until her successor has been elected and qualified, subject, however, to any earlier death, resignation, retirement, disqualification or removal.