Effective on January 22, 2021, upon recommendation of the Nominating and Corporate Governance Committee of the Board, the Board approved an increase in its authorized size from six members to eight members and appointed Bonnie Bassler, Ph.D. to fill one of the vacancies created by the board size increase and serve as a Class I director until the Company's 2022 annual meeting of stockholders and Carin Canale-Theakston to fill the other vacancy created by the board size increase and serve as a Class III director until the Company's 2021 annual meeting of stockholders. Concurrently with their appointments to the Board, Dr. Bassler was appointed to the Nominating and Corporate Governance Committee of the Board and Ms. Canale-Theakston was appointed to the Compensation Committee of the Board.