Centrexion Therapeutics Corporation announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to CNTX-4975 for the treatment of pain associated with knee osteoarthritis. CNTX-4975, Centrexion Phase 3 ready lead therapy, is a synthetic, ultra-pure injection of trans-capsaicin designed to be injected directly into the painful joint to provide rapid and durable pain relief. The FDA’s Fast Track process is designed to expedite the development and review of drugs used to treat serious conditions and fill an unmet medical need. Fast Track designation enables the company to have early and frequent communication with the FDA throughout the drug development and review process, often leading to faster drug approval and patient access. CNTX-4975 is Phase 3 ready for the treatment of two chronic pain conditions: osteoarthritis pain of the knee and pain associated with Morton’s neuroma, a rare, painful foot condition. The FDA previously granted CNTX-4975 orphan drug designation and Fast Track designation for the treatment of Morton's neuroma pain. In the Phase 2b TRIUMPH clinical trial, treatment with CNTX-4975 resulted in one of the larger reductions of pain associated with knee osteoarthritis reported in any placebo controlled clinical trial.