Synlogic, Inc. Share Price

SYBX

US87166L2097

Biotechnology & Medical Research

Market Closed - OTC Markets Other stock markets 20:56:46 31/07/2026 BST			5-day change	1st Jan Change
1.200 ^USD	+4.35%		+79.16%	+7.14%

07-29	Caldera Therapeutics, Inc. entered into an agreement and plan of merger to acquire Synlogic, Inc. for an enterprise value of approximately $500 million in a reverse merger transaction.	CI
05-14	Synlogic, Inc. Reports Earnings Results for the First Quarter Ended March 31, 2026	CI

Analysts' recommendations: Synlogic, Inc.

20/03/24	HC Wainwright Upgrades Synlogic to Neutral From Sell	MT
09/02/24	Chardan Downgrades Synlogic to Neutral From Buy on Early Termination of Synpheny-3 Trial	MT
09/02/24	Leerink Partners Downgrades Synlogic to Market Perform From Outperform, Adjusts PT to $1 From $6	MT
09/02/24	HC Wainwright Downgrades Synlogic to Sell From Buy	MT
11/12/23	Alliance Global Partners Starts Coverage on Synlogic with Buy Rating, $30 Price Target	MT

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Press Releases: Synlogic, Inc.

07-29	Synlogic and Caldera Therapeutics Announce Merger Agreement and Concurrent Private Placement	BU
23/12/24	Synlogic : Management Change/Compensation Form 8 K	PU
12/11/24	Synlogic : Reports Third Quarter 2024 Financial Results Form 8 K	PU
12/11/24	Synlogic Reports Third Quarter 2024 Financial Results	AQ
08/08/24	Synlogic Reports Second Quarter 2024 Financial Results	AQ

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Managers and Directors: Synlogic, Inc.

Manager	Title	Age	Since
Mary Dooley CEO	Chief Executive Officer	45	31/12/2024

Director	Title	Age	Since
Richard Shea BRD	Director/Board Member	74	27/08/2017
Peter Barrett CHM	Chairman	74	27/08/2017
Ed Mathers Mathers BRD	Director/Board Member	66	30/09/2012

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Other Biotechnology & Medical Research

Add to a list 0 selected To use this feature you must be a member Log in Sign up	Change	5-day change	1-year change	3-year change	Capi.($)
SYNLOGIC, INC.	+4.35%	+79.16%	-22.08%	-83.67%	14.04M
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IQVIA HOLDINGS INC.	-1.16%	+12.96%	+26.45%	+5.03%	38.68B
BEONE MEDICINES AG	-1.88%	-3.03%	+4.94%	+47.52%	35.13B
CELLTRION, INC.	-1.74%	+5.12%	+9.58%	+46.02%	29.79B
ASCENDIS PHARMA A/S	-2.85%	-3.92%	-	-	16.08B
MEDPACE HOLDINGS, INC.	-0.21%	-4.04%	+35.09%	+127.95%	16.11B
EUROFINS SCIENTIFIC SE	-0.64%	+2.65%	+1.25%	+8.92%	13.61B
ICON PUBLIC LIMITED COMPANY	-1.19%	-1.32%	-3.32%	-34.94%	12.62B
Average	-0.91%	+0.95%	+50.37%	+82.50%	25.04B
Weighted average by Cap.	-1.60%	+2.03%	+76.86%	+128.09%

See all sector performances

Synlogic, Inc. is a biopharmaceutical company advancing novel therapeutics to transform the care of serious diseases. The Company is focused on rare metabolic disorders, with its lead program, labafenogene marselecobac (SYNB1934), studied in Synpheny-3, a global, pivotal Phase 3 study for patients with phenylketonuria (PKU), and SYNB1353, a potential treatment for homocystinuria (HCU). The Company's early-stage pipeline includes product candidates for enteric hyperoxaluria, gout, and cystinuria, and has been fueled by a reproducible, proprietary approach that creates gastrointestinal (GI)-restricted, oral medicines with new enzymatic pathways designed to consume or produce specific biological targets. The Company designs, develops and manufactures these drug candidates, which are produced by applying genetic engineering to well-characterized probiotics. The Companyâ€™s preclinical work includes additional metabolic disease research.

Employees

Sector

Biotechnology & Medical Research

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Quotes

Date	Price	Change	Volume
31/07/26	US$1.200	+4.35%	300,801
30/07/26	US$1.150	+2.68%	485,293
29/07/26	US$1.120	+55.56%	2,723,780
28/07/26	US$0.7200	+7.50%	88,377
23/07/26	US$0.6698	-5.80%	1,672

Delayed Quote OTC Markets

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Income Statement and Estimates

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Annual profits - Rate of surprise

Company calendar

Market Cap	14.04M 12.2M 11.36M 10.43M 19.69M 1.34B 20M 134M 52.54M 667M 52.71M 51.56M 2.24B	P/E 2024	-0.73x	P/E 2025	-13.7x
Enterprise Value	-632K -549K -511K -470K -887K -60.33M -900K -6.03M -2.37M -30.04M -2.37M -2.32M -101M	EV / Sales 2024	-311x	EV / Sales 2025	-
Free-Float	82.47%	Yield 2024 *	-	Yield 2025	-

07-29	Caldera Therapeutics, Inc. entered into an agreement and plan of merger to acquire Synlogic, Inc. for an enterprise value of approximately $500 million in a reverse merger transaction.	CI
05-14	Synlogic, Inc. Reports Earnings Results for the First Quarter Ended March 31, 2026	CI
03-12	Synlogic, Inc. Reports Earnings Results for the Full Year Ended December 31, 2025	CI
01-23	Synlogic, Inc.(OTCPK:SYBX) dropped from S&P TMI Index	CI
01-19	Synlogic, Inc.(OTCPK:SYBX) dropped from NASDAQ Composite Index	CI
11-26	Synlogic receives letter from Nasdaq listing qualifications department on Nov 21 - SEC filing	RE
11-13	Synlogic, Inc. Reports Earnings Results for the Third Quarter and Nine Months Ended September 30, 2025	CI
08/08/25	Synlogic Inc files for mixed shelf of up to $150 million - SEC filing	RE
08/08/25	Synlogic Files $150 Million Mixed Shelf	MT
07/08/25	Synlogic, Inc. Reports Earnings Results for the Second Quarter and Six Months Ended June 30, 2025	CI
08/05/25	Synlogic, Inc. Reports Earnings Results for the First Quarter Ended March 31, 2025	CI
06/03/25	Synlogic, Inc. Reports Earnings Results for the Full Year Ended December 31, 2024	CI
21/02/25	Synlogic, Inc. Announces Resignation of Michael Heffernan as A Member of the Board of Directors and as A Member of the Audit Committee and Nominating and Governance Committee	CI

1 day	+4.35%
1 week	+79.16%
1 month	+71.18%
3 months	+90.48%
6 months	+90.48%
Current year	+7.14%

1 week	0.67	1.3
1 month	0.64	1.3
Current year	0.54	1.3
1 year	0.54	1.87
3 years	0.54	8.85
5 years	0.54	60.6
10 years	0.54	345

Date	Insider	Type	Main position	Quantity	% Market Cap.
29/10/25	Mary Dooley	Sell	Chief Executive Officer	157	0.0013%
26/04/25	James Flynn	Free	Director	15,000	0.1282%
26/04/25	Richard Shea	Free	Director	15,000	0.1282%

Synlogic, Inc. Share Price

Stocks

SYBX

US87166L2097

Biotechnology & Medical Research

Valuation: Synlogic, Inc.

Chart: Synlogic, Inc.

Latest news : Synlogic, Inc.

Analysts' recommendations: Synlogic, Inc.

Press Releases: Synlogic, Inc.

Quotes and Performance

Course Extremes

Managers and Directors: Synlogic, Inc.

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Financials

Company Profile

Quotes

Income Statement and Estimates

Annual profits - Rate of surprise

	2024	2025
Net sales	8K 6.95K 6.47K 5.94K 11.22K 764K 11.4K 76.3K 29.95K 380K 30.04K 29.38K 1.27M	-
Net income	-23.36M -20.31M -18.9M -17.35M -32.77M -2.23B -33.28M -223M -87.44M -1.11B -87.73M -85.8M -3.72B	-1M -874K -813K -747K -1.41M -95.94M -1.43M -9.59M -3.76M -47.76M -3.77M -3.69M -160M
Net Debt	-18.86M -16.39M -15.26M -14.01M -26.46M -1.8B -26.87M -180M -70.6M -896M -70.83M -69.27M -3.01B	-14.67M -12.75M -11.87M -10.9M -20.58M -1.4B -20.9M -140M -54.91M -697M -55.09M -53.88M -2.34B