Valuation: Spero Therapeutics, Inc.

Market Cap 125M 109M 101M 93.49M 177M 11.87B 180M 1.21B 470M 5.86B 470M 459M 20.25B P/E 2024
-0.81x
P/E 2025 15.5x
Enterprise Value 125M 109M 101M 93.49M 177M 11.87B 180M 1.21B 470M 5.86B 470M 459M 20.25B EV / Sales 2024
1,170,430x
EV / Sales 2025 -
Free-Float
77.54%
Yield 2024 *
-
Yield 2025 -
1 day+0.69%
1 week-1.58%
Current month-1.13%
1 month-20.26%
3 months-19.67%
6 months-14.98%
Current year-6.22%
1 week 2.12
Extreme 2.12
2.28
1 month 1.95
Extreme 1.95
3.05
Current year 1.95
Extreme 1.95
3.08
1 year 1.8
Extreme 1.8
3.22
3 years 0.51
Extreme 0.5052
3.22
5 years 0.51
Extreme 0.5052
19.87
10 years 0.51
Extreme 0.5052
23.64
Manager TitleAgeSince
Chief Executive Officer 47 09/01/2025
Chief Operating Officer 58 31/01/2023
Investor Relations Contact - -
Director TitleAgeSince
Chairman 69 31/12/2013
Director/Board Member 62 31/08/2015
Chairman 56 09/01/2025
Date Insider Type Main position Quantity % Market Cap.
06-22Free

Director

30,000 0.0518%
06-22Free

Director

30,000 0.0518%
06-22Free

Chairman

30,000 0.0518%
Change 5-day change 1-year change 3-year change Capi.($)
+0.69%-1.58%-25.68%+46.64% 125M
-1.48%+0.93%+72.59%+127.82% 57.72B
-3.80%-6.24%+67.04%+86.36% 52.65B
+1.80%+7.46%+19.60%+463.63% 24.46B
-1.97%-1.31%-16.99%-13.72% 23.84B
-3.05%+3.06%+42.36%-5.66% 19.28B
-0.24%+5.22%+38.91%-25.87% 17.8B
+2.34%+14.18%+220.96%+380.99% 17.29B
-6.73%+9.90%+36.04% - 15.28B
-2.08%+4.16%+29.18%+194.73% 14.35B
Average -1.44%+4.39%+48.40%+139.43% 24.28B
Weighted average by Cap. -1.80%+2.56%+58.03%+139.56%

Financials

2024 2025
Net sales 47.98M 41.98M 38.69M 35.86M 68.08M 4.55B 69.18M 464M 180M 2.25B 180M 176M 7.77B 66.8M 58.46M 53.88M 49.94M 94.79M 6.34B 96.32M 646M 251M 3.13B 251M 245M 10.82B
Net income -68.57M -60M -55.3M -51.25M -97.3M -6.51B -98.87M -663M -258M -3.21B -257M -252M -11.1B 8.57M 7.5M 6.91M 6.41M 12.16M 814M 12.36M 82.9M 32.24M 402M 32.18M 31.48M 1.39B
Net Debt - -
Logo Spero Therapeutics, Inc.
Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant (MDR) bacterial infections with unmet need. Its product candidate SPR720 is an investigational, chemically stable phosphate ester prodrug that is converted in vivo to SPR719 for the treatment of nontuberculous mycobacterial (NTM) pulmonary disease. Its clinical stage product candidate, tebipenem HBr is an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTIs) including acute pyelonephritis (AP) to help patients potentially reduce duration of in-patient therapy.
Employees
25
Date Price Change Volume
08/07/26 US$2.185 +1.16% 106,043
07/07/26 US$2.160 -1.37% 879,844
06/07/26 US$2.190 -0.45% 372,735
02/07/26 US$2.200 -0.90% 629,524
01/07/26 US$2.220 +0.45% 397,551
Sell
Consensus
Buy
Mean consensus
HOLD
Number of Analysts
1
Last Close Price
2.160USD
Average target price
4.000USD
Spread / Average Target
+85.19%

Quarterly revenue - Rate of surprise

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