Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant (MDR) bacterial infections with unmet need. Its product candidate SPR720 is an investigational, chemically stable phosphate ester prodrug that is converted in vivo to SPR719 for the treatment of nontuberculous mycobacterial (NTM) pulmonary disease. Its clinical stage product candidate, tebipenem HBr is an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTIs) including acute pyelonephritis (AP) to help patients potentially reduce duration of in-patient therapy.

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Biotechnology & Medical Research

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Quotes

Date	Price	Change	Volume
17/07/26	US$1.580	+0.64%	1,249,349
16/07/26	US$1.570	-7.65%	2,627,725
15/07/26	US$1.700	0.00%	1,425,250
14/07/26	US$1.700	-22.02%	11,306,840
13/07/26	US$2.180	+3.81%	703,993

Delayed Quote Nasdaq

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Sell

Buy

Mean consensus

HOLD

Number of Analysts

Last Close Price

1.580USD

Average target price

4.000USD

Spread / Average Target

+153.16%

Consensus

EPS Estimates

Revisions to estimates

Quarterly revenue - Rate of surprise

Company calendar

Market Closed - Nasdaq Other stock markets 21:00:00 17/07/2026 BST			5-day change	1st Jan Change
1.580 ^USD	+0.64%		-24.76%	-32.19%

07-15	Innovent Biologics Shares Surge on Spero Deal That Could Be Worth $1.1 Billion	DJ
07-14	Innovent Biologics, Inc. and Spero Therapeutics, Inc. Announce Exclusive License Agreement for IBI355, Phase 2-Ready Third-Generation Anti-CD40L Antibody	CI

Market Cap	91.48M 79.95M 73.77M 68M 128M 8.81B 131M 882M 347M 4.31B 344M 336M 14.85B	P/E 2024	-0.81x	P/E 2025	15.5x
Enterprise Value	91.48M 79.95M 73.77M 68M 128M 8.81B 131M 882M 347M 4.31B 344M 336M 14.85B	EV / Sales 2024	1,170,430x	EV / Sales 2025	-
Free-Float	77.54%	Yield 2024 *	-	Yield 2025	-

07-15	Innovent Biologics Shares Surge on Spero Deal That Could Be Worth $1.1 Billion	DJ
07-14	Innovent Biologics, Inc. and Spero Therapeutics, Inc. Announce Exclusive License Agreement for IBI355, Phase 2-Ready Third-Generation Anti-CD40L Antibody	CI
07-14	Spero Therapeutics Licenses Immunology Drug Candidate From Innovent, Recieves $105 Million Financing	MT
07-14	Spero licenses Innovent's experimental immune disease drug for up to $1.1 billion	RE
06-29	Spero Therapeutics, Inc.(NasdaqGS:SPRO) added to Russell 3000E Growth Benchmark	CI
06-29	Spero Therapeutics, Inc.(NasdaqGS:SPRO) added to Russell 3000E Index	CI
06-29	Spero Therapeutics, Inc.(NasdaqGS:SPRO) added to Russell Microcap Index	CI
06-28	Spero Therapeutics, Inc.(NasdaqGS:SPRO) added to Russell Microcap Growth Benchmark Index	CI
06-17	GSK says US FDA approves urinary tract infection treatment Utebzi	AN
06-17	GSK plc Receives US FDA Approval for Oral Antibiotic Tebipenem for Complicated Urinary Tract Infections	CI
06-17	GSK Secures US FDA Nod for Complicated Urinary Tract Infection Antibiotic	MT
06-17	GSK, Spero Therapeutics Get FDA Approval for Utebzi in Complicated Urinary Tract Infections	MT
06-17	GSK, Spero Therapeutics Gain U.S. Approval for Utebzi	DJ

21/10/25	Spero Therapeutics, Inc. and Gsk plc Announces Efficacy and Safety Results of the Positive Pivot-Po Trial Evaluating Tebipenem Hbr	CI
20/12/24	Evercore ISI Downgrades Spero Therapeutics to In Line From Outperform, Price Target is $5	MT
18/11/24	TD Cowen Downgrades Spero Therapeutics to Hold From Buy	MT
06/08/24	TD Cowen Upgrades Spero Therapeutics to Buy From Hold	MT
14/08/23	HC Wainwright Adjusts Price Target on Spero Therapeutics to $7 From $6, Keeps Buy Rating	MT

Spero Therapeutics, Inc. Share Price

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SPRO

US84833T1034

Biotechnology & Medical Research

Valuation: Spero Therapeutics, Inc.

Chart: Spero Therapeutics, Inc.

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Quotes and Performance

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Managers and Directors: Spero Therapeutics, Inc.

Latest insider transactions

Bio Therapeutic Drugs

Financials

Company Profile

Quotes

Income Statement and Estimates

Analysts' Consensus

Quarterly revenue - Rate of surprise

07-14	Spero Therapeutics Announces $105 Million Non-Recourse Non-Dilutive Financing Backed by a Portion of Utebzi Milestones & Royalties	AQ
07-14	Spero Therapeutics and Innovent Biologics Announce Exclusive License for SP001 (IBI355), a Phase 2-Ready Third-Generation Anti-CD40L Antibody	AQ
05-13	Spero Therapeutics Announces First Quarter 2026 Operating Results and Provides Business Update	AQ
05-05	Spero Therapeutics to Report First Quarter 2026 Financial Results and Provide Business Update on May 13, 2026	AQ
03-26	Spero Therapeutics Announces Fourth Quarter and Full Year 2025 Operating Results and Provides a Business Update	AQ

06-18	Bourse : L'Oréal met le cap sur l'Inde, gros contrat pour Alstom, rumeur sur Edenred
06-18	Star Warsh
06-18	MORNING BRIEFING - Deutschland/Europa -2-
06-17	GSK und Spero Therapeutics erhalten US-Zulassung für Utebzi
21/10/25	GSK et Spero publient des résultats positifs sur un antibiotique expérimental

1 day	+0.64%
1 week	-24.76%
Current month	-28.51%
1 month	-30.70%
3 months	-42.55%
6 months	-34.44%
Current year	-32.19%

1 week	1.5	2.34
1 month	1.5	2.36
Current year	1.5	3.08
1 year	1.5	3.08
3 years	0.51	3.22
5 years	0.51	19.87
10 years	0.51	23.64

Manager	Title	Age	Since
Esther Rajavelu CEO	Chief Executive Officer	47	09/01/2025
Timothy Keutzer COO	Chief Operating Officer	58	31/01/2023
Shai Biran IRC	Investor Relations Contact	-	-

Director	Title	Age	Since
Milind Deshpande CHM	Chairman	69	31/12/2013
Patrick Volkert Vink BRD	Director/Board Member	62	31/08/2015
Frank Thomas CHM	Chairman	56	09/01/2025

Date	Insider	Type	Main position	Quantity	% Market Cap.
23/06/26	Kathleen Tregoning	Free	Director	30,000	0.0518%
23/06/26	Frank Thomas	Free	Chairman	30,000	0.0518%
23/06/26	John Pottage	Free	Director	30,000	0.0518%

Add to a list 0 selected To use this feature you must be a member Log in Sign up	Change	5-day change	1-year change	3-year change	Capi.($)
SPERO THERAPEUTICS, INC.	+0.64%	-24.76%	-33.33%	+5.33%	91.48M
ARGENX SE	+0.24%	-1.54%	+52.85%	+71.85%	53.83B
WUXI APPTEC CO., LTD.	-7.17%	-4.39%	+42.72%	+73.32%	52.1B
INSMED INCORPORATED	+0.80%	-6.31%	+5.62%	+417.78%	23.48B
BIONTECH SE	-0.09%	-0.01%	-16.85%	-15.41%	23.13B
WUXI BIOLOGICS (CAYMAN) INC.	-5.95%	-2.58%	+29.53%	-9.47%	19.36B
GENMAB A/S	-1.14%	+0.03%	+31.67%	-30.65%	17.56B
PHARMAESSENTIA CORPORATION	-5.16%	-7.00%	+168.44%	+314.96%	15.2B
SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.	-6.91%	-5.83%	+25.17%	+644.30%	14.83B
EXELIXIS, INC.	+0.43%	-1.03%	+25.75%	+189.74%	14.06B
Average	-2.43%	-4.84%	+33.16%	+166.17%	23.36B
Weighted average by Cap.	-2.80%	-2.36%	+39.52%	+143.07%

	2024	2025
Net sales	47.98M 41.93M 38.69M 35.66M 67.22M 4.62B 68.71M 462M 182M 2.26B 180M 176M 7.79B	66.8M 58.38M 53.87M 49.65M 93.59M 6.43B 95.67M 644M 253M 3.15B 251M 245M 10.85B
Net income	-68.57M -59.92M -55.29M -50.97M -96.06M -6.6B -98.19M -661M -260M -3.23B -257M -252M -11.13B	8.57M 7.49M 6.91M 6.37M 12.01M 825M 12.28M 82.62M 32.5M 404M 32.19M 31.49M 1.39B
Net Debt	-	-