GT Biopharma, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of immuno-oncology therapeutic products based on its proprietary Tri-specific Killer Engager (TriKE) natural killer (NK) cell engager platform. Its TriKE platform is designed to harness and enhance the cancer-killing abilities of a patientâ€™s immune systemâ€™s natural killer cells. Its product candidate pipeline includes GTB-3550, GTB-3650, GTB-5550, GTB-7550, GTB-6550, GTB-1050, and other product candidates. GTB-3550 is a TriKE comprised of two single-chain variable fragments (scFv) composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of IL-15. GTB-3650 is a TriKE which targets CD33 on the surface of myeloid leukemias. The Company also has a worldwide license agreement with the University of Minnesota to further develop and commercialize therapies using TriKE technology.

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Biotechnology & Medical Research

More about the company

06-30	GT Biopharma Reports Integration Of AI-Based Tools Across Discovery And Engineering Of Tumor-Targeting NK Cell Engagers And Multi-Domain Proteins	CI
06-08	Gt Biopharma Advances Three Trike Drug Candidates into Human Trials and Doses First Patient in Phase 1 Trial of Gtb-5550	CI

Market Cap	12.83M 11.25M 10.4M 9.56M 18.04M 1.24B 18.33M 124M 48.74M 606M 48.19M 47.14M 2.09B	P/E 2026 *	-1.05x	P/E 2027 *	-1.32x
Enterprise Value	12.83M 11.25M 10.4M 9.56M 18.04M 1.24B 18.33M 124M 48.74M 606M 48.19M 47.14M 2.09B	EV / Sales 2026 *	-	EV / Sales 2027 *	-
Free-Float	93.99%	Yield 2026 *	-	Yield 2027 *	-

06-30	GT Biopharma Reports Integration Of AI-Based Tools Across Discovery And Engineering Of Tumor-Targeting NK Cell Engagers And Multi-Domain Proteins	CI
06-08	Gt Biopharma Advances Three Trike Drug Candidates into Human Trials and Doses First Patient in Phase 1 Trial of Gtb-5550	CI
06-01	GT Biopharma, Inc. Provides Update on Pipeline Discovery Activities from Newly Implemented AI-Based Technological Initiatives	CI
05-29	GT Biopharma Advances Three Trike Drug Candidates into Human Trials	CI
05-15	GT Biopharma, Inc. Reports Earnings Results for the First Quarter Ended March 31, 2026	CI
05-14	GT Biopharma announces first patient dosed in phase 1 trial of GTB-5550, a B7-H3-targeted natural killer (NK) cell engager for solid tumors	RE
05-14	Gt Biopharma Inc Announces First Patient Dosed in Phase 1 Trial of Gtb-5550, A B7-H3-Targeted Natural Killer (Nk) Cell Engager for Solid Tumors	CI
04-07	GT Biopharma, Inc. Enters into Investigator Initiated Clinical Trial Agreement with Regents of the University of Minnesota	CI
03-02	GT Biopharma, Inc. Reports Earnings Results for the Full Year Ended December 31, 2025	CI
03-01	GT Biopharma, Inc. Auditor Raises 'Going Concern' Doubt	CI
02-03	GT Biopharma, Inc. Announces FDA Clearance of Investigational New Drug for GTB-5550 TriKE, B7-H3-Targeted Natural Killer Cell Engager for Solid Tumors Expressing B7-H3	CI
02-03	GT Biopharma gets FDA IND clearance for GTB-5550 TRiKE, B7-H3-targeted NK engager for B7-H3+ solid tumors	RE
01-15	GT Biopharma, Inc. Announces IND Submission for GTB-5550 TriKE, B7-H3-Targeted Natural Killer Cell Engager for B7-H3 Expressing Solid Tumor Cancers	CI

05/01/23	EF Hutton Starts GT Biopharma at Hold With $2 Price Target	MT
13/09/22	HC Wainwright Adjusts Price Target on GT Biopharma to $5 From $25, Reiterates Buy Rating	MT
12/08/22	Roth Capital Cuts GT Biopharma to Neutral From Buy, Price Target to $3 From $9	MT
24/01/22	B. Riley Lowers GT Biopharma's Price Target to $18 from $26 After Revising Cost Capital Assumptions, Keeps Buy Rating	MT
24/06/21	GT BIOPHARMA : B. Riley Raises GT Biopharma's PT to $26 from $21, Notes Steady Progress of Dose-Escalation Trial of Lead Asset GTB-3550; Keeps Buy Rating	MT

06-30	A Clinical-Stage Cancer Company Is Putting AI to Work Designing Its Next Generation of Tumor-Targeting Drugs	AQ
06-12	After CAR-T, the Next Frontier in Cancer Immunotherapy May Belong to a Different Immune Cell	AQ
06-08	Three Cancer Drugs Have Reached the Clinic: Inside GT Biopharma's TriKE Bet	AQ
06-01	GT Biopharma Provides Update on Pipeline Discovery Activities from Newly Implemented AI-Based Technological Initiatives	AQ
05-15	GT Biopharma Reports First Quarter 2026 Financial Results	AQ

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Manager	Title	Age	Since
Michael Breen CEO	Chief Executive Officer	64	01/03/2022
Alan Urban DFI	Director of Finance/CFO	57	02/06/2024

Director	Title	Age	Since
Michael Breen CHM	Chairman	64	14/12/2021
Charles Casamento BRD	Director/Board Member	81	30/04/2023
Hilary Kramer BRD	Director/Board Member	62	06/05/2025

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Average	+1.31%	-2.44%	+42.71%	+181.11%	25.95B
Weighted average by Cap.	+1.73%	-2.34%	+42.69%	+140.37%

	2026 *	2027 *
Net sales	-	-
Net income	-12.27M -10.75M -9.94M -9.14M -17.25M -1.18B -17.53M -119M -46.59M -579M -46.07M -45.07M -1.99B	-12.7M -11.13M -10.29M -9.46M -17.85M -1.22B -18.14M -123M -48.23M -599M -47.68M -46.64M -2.06B
Net Debt	-	-

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