Valuation: Karyopharm Therapeutics Inc.

Market Cap 44.19M 38.35M 35.91M 32.85M 62.01M 4.21B 62.82M 420M 165M 2.1B 166M 162M 7B P/E 2026 *
-0.45x
P/E 2027 * -0.72x
Enterprise Value 44.19M 38.35M 35.91M 32.85M 62.01M 4.21B 62.82M 420M 165M 2.1B 166M 162M 7B EV / Sales 2026 *
0.33x
EV / Sales 2027 * 0.25x
Free-Float
95.32%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day+2.09%
1 week-72.18%
Current month+1.56%
1 month-79.73%
3 months-78.38%
6 months-68.85%
Current year-73.51%
1 week 1.8
Extreme 1.8
2.11
1 month 1.8
Extreme 1.8
10.86
Current year 1.8
Extreme 1.8
10.99
1 year 1.8
Extreme 1.8
10.99
3 years 1.8
Extreme 1.8
29.25
5 years 1.8
Extreme 1.8
220.95
10 years 1.8
Extreme 1.8
444.15
Manager TitleAgeSince
Chief Executive Officer 58 02/05/2021
Director of Finance/CFO 55 02/01/2025
Chief Tech/Sci/R&D Officer - 31/03/2023
Director TitleAgeSince
Director/Board Member 62 31/12/2012
Director/Board Member 61 31/03/2013
Director/Board Member 78 02/10/2013
Date Insider Type Main position Quantity % Market Cap.
28/07/26 Sell

Executive/Senior Manager

-189 0.0008%
14/05/26 Sell

Controller/Auditor

-53 0.0002%
17/02/26 Sell

Executive/Senior Manager

378 0.0021%
Change 5-day change 1-year change 3-year change Capi.($)
+2.09%-72.18%-51.61%-92.44% 44.19M
+0.46%+4.57%+39.09%+0.74% 77.1B
+1.07%+2.11%+23.36%+184.78% 49.43B
+1.54%-0.85%-4.49%+23.71% 49.27B
-0.13%+7.42%-50.22%-49.58% 44.59B
-0.17%-0.79%+59.49%-23.29% 30.48B
-1.19%-3.75%+52.45%+86.04% 24B
-4.26%-7.01%+101.65%-50.22% 21.5B
+4.29%+9.40%+3.77%+226.51% 20.18B
+1.26%-3.95%+64.96%+123.32% 16.29B
Average +0.51%-7.25%+23.85%+42.96% 33.29B
Weighted average by Cap. +0.43%+1.47%+24.32%+45.06%

Financials

2026 *2027 *
Net sales 134M 116M 109M 99.41M 188M 12.74B 190M 1.27B 499M 6.37B 502M 491M 21.19B 175M 152M 142M 130M 245M 16.63B 248M 1.66B 651M 8.31B 656M 641M 27.66B
Net income -118M -102M -95.91M -87.73M -166M -11.24B -168M -1.12B -440M -5.62B -443M -434M -18.7B -105M -91.04M -85.24M -77.98M -147M -9.99B -149M -997M -391M -4.99B -394M -385M -16.62B
Net Debt - -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
06/08/26 US$1.950 +2.09% 1,189,123
05/08/26 US$1.910 -2.55% 2,376,615
04/08/26 US$1.960 -0.51% 3,792,123
03/08/26 US$1.970 +2.60% 4,514,606
31/07/26 US$1.920 -72.61% 22,398,319
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
OUTPERFORM
Number of Analysts
6
Last Close Price
1.950USD
Average target price
6.400USD
Spread / Average Target
+228.21%

Quarterly revenue - Rate of surprise

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