Valuation: Karyopharm Therapeutics Inc.

Market Cap 161M 141M 131M 121M 226M 15.35B 230M 1.56B 610M 7.61B 603M 590M 26.3B P/E 2026 *
-1.71x
P/E 2027 * -2.04x
Enterprise Value 414M 363M 338M 311M 583M 39.52B 593M 4.01B 1.57B 19.6B 1.55B 1.52B 67.72B EV / Sales 2026 *
2.99x
EV / Sales 2027 * 1.08x
Free-Float
95.32%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day-1.62%
1 week-11.00%
Current month-28.35%
1 month-30.59%
3 months-18.60%
6 months+1.16%
Current year-4.89%
1 week 6.75
Extreme 6.75
8.02
1 month 6.48
Extreme 6.485
10.86
Current year 5
Extreme 5
10.99
1 year 3.65
Extreme 3.6503
10.99
3 years 3.51
Extreme 3.51
29.25
5 years 3.51
Extreme 3.51
220.95
10 years 3.51
Extreme 3.51
444.15
Manager TitleAgeSince
Chief Executive Officer 58 02/05/2021
Director of Finance/CFO 55 02/01/2025
Chief Tech/Sci/R&D Officer - 31/03/2023
Director TitleAgeSince
Director/Board Member 62 31/12/2012
Director/Board Member 61 31/03/2013
Director/Board Member 78 02/10/2013
Date Insider Type Main position Quantity % Market Cap.
21/05/26 Free

Director

15,508 0.0688%
21/05/26 Free

Director

15,508 0.0688%
21/05/26 Free

Director

15,508 0.0688%
Change 5-day change 1-year change 3-year change Capi.($)
-1.48%-11.00%+60.18%-74.07% 161M
+3.26%+1.84%+23.09%-7.84% 67.88B
+1.79%+2.58%+39.89%+213.85% 53.23B
+0.26%+54.90%+54.90%+54.90% 48.71B
+2.69%-2.52%-55.39%-55.35% 38.98B
+1.16%-0.38%+56.54%-23.70% 29.55B
+8.24%+11.39%+86.37%+107.26% 23.75B
-0.73%-7.29%+63.11%-53.39% 22.07B
+0.62%-2.81%+0.84%+162.10% 19.84B
+0.60%+0.39%+65.65%+126.60% 16.57B
Average +1.61%-0.15%+39.52%+45.04% 32.07B
Weighted average by Cap. +2.05%+1.30%+32.53%+54.05%

Financials

2026 *2027 *
Net sales 138M 121M 113M 104M 195M 13.2B 198M 1.34B 525M 6.55B 519M 508M 22.62B 149M 131M 122M 112M 210M 14.23B 214M 1.44B 565M 7.06B 559M 547M 24.39B
Net income -116M -102M -95.11M -87.48M -164M -11.12B -167M -1.13B -442M -5.51B -437M -427M -19.05B -142M -125M -116M -107M -200M -13.57B -204M -1.38B -539M -6.73B -533M -522M -23.25B
Net Debt 253M 222M 207M 190M 356M 24.17B 363M 2.45B 960M 11.99B 950M 929M 41.42B -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
28/07/26 US$6.960 -1.83% 188,747
27/07/26 US$7.090 -4.32% 527,473
24/07/26 US$7.410 +4.51% 900,248
23/07/26 US$7.090 -1.25% 680,130
22/07/26 US$7.180 -8.71% 713,636
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
6
Last Close Price
7.090USD
Average target price
14.80USD
Spread / Average Target
+108.74%

Quarterly revenue - Rate of surprise

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