Valuation : Karyopharm Therapeutics Inc.

Market Cap 40.6M 34.91M 32.84M 29.97M 55.93M 3.85B 56.22M 389M 151M 1.97B 152M 149M 6.26B P/E 2026 *
-0.38x
P/E 2027 * -0.75x
Enterprise Value 40.6M 34.91M 32.84M 29.97M 55.93M 3.85B 56.22M 389M 151M 1.97B 152M 149M 6.26B EV / Sales 2026 *
0.3x
EV / Sales 2027 * 0.23x
Free-Float
95.33%
Yield 2026 *
-
Yield 2027 * -

Last Transcript : Karyopharm Therapeutics Inc.

1 day-4.75%
1 week-7.57%
Current month-16.99%
1 month-12.76%
3 months-79.88%
6 months-79.86%
Current year-76.77%
1 week 1.7
Extreme 1.7001
1.94
1 month 1.7
Extreme 1.7001
2.18
Current year 1.7
Extreme 1.7001
10.99
1 year 1.7
Extreme 1.7001
10.99
3 years 1.7
Extreme 1.7001
29.25
5 years 1.7
Extreme 1.7001
220.95
10 years 1.7
Extreme 1.7001
444.15
Manager TitleAgeSince
Chief Executive Officer 58 02/05/2021
Director of Finance/CFO 55 02/01/2025
Chief Tech/Sci/R&D Officer - 31/03/2023
Director TitleAgeSince
Director/Board Member 62 31/12/2012
Director/Board Member 61 31/03/2013
Director/Board Member 78 02/10/2013
Date Insider Type Main position Quantity % Market Cap. Importance
01/09/26 Sell

Controller/Auditor

-19 0.0001%
28/07/26 Sell

Executive/Senior Manager

-189 0.0008%
21/05/26 Free

Director

15,508 0.0688%
Change 5-day change 1-year change 3-year change Capi.($)
-4.19%-7.57%-72.64%-90.26% 40.6M
-1.57%-1.34%+45.54%-2.16% 82.65B
+0.94%+1.88%-16.46%-34.82% 59.87B
-1.93%-7.24%+476.32%+32.94% 58.11B
-1.77%-5.14%-9.07%+29.36% 50.35B
-1.62%-5.31%-1.66%+150.73% 46.62B
-3.02%-0.84%+51.55%-17.29% 32.63B
-0.62%+0.49%+45.12%+96.34% 25.69B
-1.09%-3.47%-2.81%+183.45% 22.49B
+1.56%-0.09%+65.58%+110.60% 16.33B
Average -1.39%+0.06%+58.15%+45.89% 39.48B
Weighted average by Cap. -1.18%+1.12%+85.54%+40.52%

Financials

2026 *2027 *
Net sales 136M 117M 110M 100M 187M 12.86B 188M 1.3B 503M 6.57B 509M 498M 20.91B 174M 149M 140M 128M 239M 16.45B 240M 1.66B 644M 8.41B 652M 638M 26.76B
Net income -160M -138M -130M -118M -221M -15.18B -222M -1.54B -594M -7.76B -601M -588M -24.7B -115M -98.79M -92.94M -84.81M -158M -10.89B -159M -1.1B -426M -5.57B -431M -422M -17.72B
Net Debt - -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
08/09/26 US$1.700 -5.02% 690,623
04/09/26 US$1.790 +1.13% 577,786
03/09/26 US$1.770 -1.12% 819,676
02/09/26 US$1.790 -3.24% 1,296,285
01/09/26 US$1.850 -10.19% 1,598,051
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
5
Last Close Price
1.790USD
Average target price
7.250USD
Spread / Average Target
+305.03%

Quarterly revenue - Rate of surprise

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