Valuation: Karyopharm Therapeutics Inc.

Market Cap 18.2M 16.17M 15.09M 13.75M 25.94M 1.75B 26.18M 183M 70.76M 894M 68.31M 66.83M 2.87B P/E 2026 *
-0.17x
P/E 2027 * -0.34x
Enterprise Value 18.2M 16.17M 15.09M 13.75M 25.94M 1.75B 26.18M 183M 70.76M 894M 68.31M 66.83M 2.87B EV / Sales 2026 *
0.13x
EV / Sales 2027 * 0.1x
Free-Float
95.33%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day-7.45%
1 week-50.48%
Current month-34.25%
1 month-54.68%
3 months-91.64%
6 months-86.38%
Current year-89.10%
1 week 0.75
Extreme 0.7471
1.66
1 month 0.75
Extreme 0.7471
1.93
Current year 0.75
Extreme 0.7471
10.99
1 year 0.75
Extreme 0.7471
10.99
3 years 0.75
Extreme 0.7471
29.25
5 years 0.75
Extreme 0.7471
220.95
10 years 0.75
Extreme 0.7471
444.15
Manager TitleAgeSince
Chief Executive Officer 58 02/05/2021
Director of Finance/CFO 55 02/01/2025
Chief Tech/Sci/R&D Officer - 31/03/2023
Director TitleAgeSince
Director/Board Member 63 31/12/2012
Director/Board Member 61 31/03/2013
Director/Board Member 78 02/10/2013
Date Insider Type Main position Quantity % Market Cap. Importance
01/09/26 Sell

Controller/Auditor

-19 0.0001%
28/07/26 Sell

Executive/Senior Manager

-189 0.0008%
21/05/26 Free

Director

15,508 0.0688%
Change 5-day change 1-year change 3-year change Capi.($)
-7.45%-50.48%-87.43%-95.84% 18.2M
-0.61%-3.43%+36.07%+117.61% 1,019B
-1.02%-5.60%+35.72%+64.82% 617B
+1.11%-0.58%+12.36%+78.27% 464B
+0.34%-3.01%+61.79%+41.79% 356B
-0.95%-4.05%+20.54%+40.33% 333B
-1.46%-2.89%+10.57%+26.54% 267B
-1.35%-5.43%-6.17%+8.82% 244B
-1.04%-2.79%+35.30%+54.42% 218B
-1.87%-4.10%+28.44%+97.54% 179B
Average -1.43%-8.10%+14.72%+43.43% 369.72B
Weighted average by Cap. -0.60%-3.33%+29.07%+71.15%

Financials

2026 *2027 *
Net sales 136M 121M 112M 103M 193M 13.04B 195M 1.36B 527M 6.67B 509M 498M 21.39B 174M 154M 144M 131M 247M 16.69B 250M 1.74B 675M 8.53B 652M 638M 27.38B
Net income -160M -142M -133M -121M -228M -15.4B -230M -1.61B -623M -7.87B -601M -588M -25.26B -115M -102M -95.28M -86.84M -164M -11.05B -165M -1.15B -447M -5.65B -431M -422M -18.12B
Net Debt - -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
02/10/26 US$0.8022 -7.45% 2,341,758
01/10/26 US$0.8668 -28.95% 2,659,950
30/09/26 US$1.220 +1.24% 1,754,326
29/09/26 US$1.205 -25.62% 1,870,182
28/09/26 US$1.620 0.00% 331,072
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
5
Last Close Price
0.8022USD
Average target price
7.250USD
Spread / Average Target
+803.76%

Quarterly revenue - Rate of surprise

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