Valuation: Centessa Pharmaceuticals plc

Capitalization 3.69B 3.14B 2.91B 2.72B 5.07B 339B 5.37B 33.26B 13.2B 160B 13.84B 13.56B 582B P/E ratio 2025 *
-18.3x
P/E ratio 2026 * -15.8x
Enterprise value 3.43B 2.92B 2.71B 2.53B 4.71B 315B 5B 30.92B 12.28B 149B 12.87B 12.61B 542B EV / Sales 2025 *
218x
EV / Sales 2026 * 1,771x
Free-Float
86.58%
Yield 2025 *
-
Yield 2026 * -
More valuation ratios * Estimated data
Dynamic Chart
1 day+2.52%
1 week+13.83%
Current month+1.04%
1 month+0.04%
3 months+4.68%
6 months+62.30%
Current year+1.04%
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1 week 21.5
Extreme 21.5
26
1 month 21.5
Extreme 21.5
26
Current year 21.5
Extreme 21.5
26
1 year 9.6
Extreme 9.6
30.58
3 years 3
Extreme 3
30.58
5 years 2.88
Extreme 2.885
30.58
10 years 2.88
Extreme 2.885
30.58
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Manager TitleAgeSince
Chief Executive Officer 40 31/12/2025
Director of Finance/CFO 53 09/06/2024
Chief Tech/Sci/R&D Officer 61 07/01/2025
Director TitleAgeSince
Chairman 56 31/10/2020
Director/Board Member - 31/12/2020
Director/Board Member 53 31/12/2020
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Change 5d. change 1-year change 3-years change Capi.($)
+2.52%+13.83%+55.22%+552.97% 3.69B
+0.04%-0.68%-4.77%+12.20% 49.48B
-1.56%-1.00%+14.23%+2.87% 40.07B
+0.15%+0.33%+52.68%+26.14% 37.55B
+1.92%+1.44%+23.10%+42.46% 31.67B
-0.99%-2.20%+185.93%+328.06% 22.74B
-3.01%-3.74%+69.03%+145.51% 16.56B
Average -0.13%+1.59%+56.49%+158.60% 28.82B
Weighted average by Cap. -0.28%-0.02%+42.72%+74.13%
See all sector performances

Financials

2025 *2026 *
Net sales 15.71M 13.36M 12.38M 11.57M 21.57M 1.44B 22.86M 142M 56.18M 681M 58.9M 57.69M 2.48B 1.9M 1.62M 1.5M 1.4M 2.61M 175M 2.77M 17.12M 6.8M 82.42M 7.12M 6.98M 300M
Net income -182M -155M -144M -134M -251M -16.77B -266M -1.64B -653M -7.92B -684M -670M -28.79B -231M -197M -182M -170M -317M -21.24B -336M -2.08B -827M -10.03B -867M -849M -36.48B
Net Debt -259M -221M -204M -191M -356M -23.83B -378M -2.34B -928M -11.25B -973M -953M -40.93B -327M -278M -258M -241M -449M -30.01B -476M -2.94B -1.17B -14.17B -1.22B -1.2B -51.55B
More financial data * Estimated data
Logo Centessa Pharmaceuticals plc
Centessa Pharmaceuticals plc is a United Kingdom-based clinical-stage pharmaceutical company. Its advanced programs include a hemophilia program, an orexin agonist program for the treatment of narcolepsy and other sleep-wake disorders, and an immuno-oncology program focused on its LockBody technology platform. SerpinPC, its advanced product candidate, is an investigational, potentially first-in-class subcutaneously administered novel inhibitor of activated protein C for hemophilia. Its Orexin Receptor 2 (OX2R) Agonist Program includes ORX750, which is an investigational, orally administered, selective OX2R agonist designed to directly target the underlying pathophysiology of orexin neuron loss in narcolepsy type 1 and to address sleep-wake disorders with normal orexin levels such as narcolepsy type 2 and idiopathic hypersomnia. It is also exploring follow-up orexin agonists for potential expansion opportunities into a range of sleep-wake disorders and broader neurological indications.
Employees
114
More about the company
Date Price Change Volume
23/01/26 25.27 $ +2.52% 1,887,863
22/01/26 24.65 $ +6.11% 2,037,770
21/01/26 23.23 $ +1.35% 6,463,853
20/01/26 22.92 $ +3.24% 638,908
16/01/26 22.20 $ -0.89% 1,681,099

Delayed Quote Nasdaq, January 23, 2026 at 09:00 pm

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Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
14
Last Close Price
25.27USD
Average target price
39.23USD
Spread / Average Target
+55.25%
Consensus

Quarterly revenue - Rate of surprise