Aptose Biosciences Inc. is a clinical-stage biotechnology company focused on developing precision medicines addressing unmet medical needs in oncology, with an initial focus on hematology. The Companyâ€™s lead clinical-stage, oral kinase inhibitor tuspetinib (TUS) has demonstrated activity as a monotherapy and in combination therapy in patients with relapsed or refractory acute myeloid leukemia (AML) and is being developed as a frontline triplet therapy in newly diagnosed AML. The Company's small molecule cancer therapeutics pipeline includes products designed to provide single agent efficacy and to enhance the efficacy of anti-cancer therapies and regimens without overlapping toxicities. Its Luxeptinib (LUX) is being developed for the treatment of patients with certain B-cell malignancies, including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and certain non-Hodgkinâ€™s lymphomas (NHL) who are resistant or intolerant to conventional treatments.

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Market Cap	4.31M 3.79M 3.51M 3.23M 6.1M 412M 6.23M 41.89M 16.38M 203M 16.19M 15.84M 700M	P/E 2024	-0.19x	P/E 2025	-0.15x
Enterprise Value	30.59M 26.87M 24.91M 22.91M 43.29M 2.92B 44.22M 297M 116M 1.44B 115M 112M 4.97B	EV / Sales 2024	-	EV / Sales 2025	-
Free-Float	72.64%	Yield 2024 *	-	Yield 2025	-

07-02	Hanmi Pharmaceutical Closes Acquisition of Aptose Biosciences	MT
06-29	Hanmi Pharm. Co., Ltd. completed the acquisition of remaining 80.07% stake in Aptose Biosciences Inc..	CI
06-15	Aptose Biosciences Inc. Presents Safety, Response and MRD Clinical Data from TUSCANY Phase 1/2 Clinical Trial of Tuspetinib Triplet Therapy in Newly Diagnosed AML	CI
06-15	Aptose Biosciences Updated Tuscany Trial Data Reported in Oral Presentation at EHA 2026	MT
05-29	Aptose Biosciences Says Acquisition by Hanmi Delayed Until June	MT
05-29	Aptose Biosciences says closing of arrangement with Hanmi Pharmaceutical further delayed	RE
05-13	Aptose Biosciences Inc. Reports Earnings Results for the First Quarter Ended March 31, 2026	CI
03-31	Aptose Shareholders Approve Acquisition By Hanmi Pharmaceutical in "Go Private" Transaction	MT
03-31	Aptose Biosciences Inc. Reports Earnings Results for the Full Year Ended December 31, 2025	CI
03-31	Aptose Biosciences Inc. - Shareholder/Analyst Call
03-30	Aptose Biosciences Inc. Auditor Raises 'Going Concern' Doubt	CI
03-23	Leading independent proxy advisory firm Glass Lewis endorses Aptose plan of arrangement	RE
03-23	Aptose Biosciences Brief: Independent Proxy Advisory Firm Glass Lewis Endorses Aptose Plan of Arrangement With Hanmi Pharmaceutical	MT

03-19	Leading independent proxy advisory firm ISS recommends Aptose Biosciences shareholders vote "for" proposed plan of arrangement with Hanmi Pharmaceutical	RE
03-19	Aptose Brief: Independent Proxy Advisory Firm ISS Recommends Aptose Shareholders Vote "FOR" Proposed Plan of Arrangement with Hanmi Pharmaceutical	MT
11/06/24	HC Wainwright Adjusts Price Target on Aptose Biosciences to $7 From $23, Maintains Buy Rating	MT
10/11/23	RBC Cuts Price Target on Aptose Biosciences to $18 From $23, Keeps Outperform, Speculative Risk	MT
11/08/23	Oppenheimer Adjusts Aptose Biosciences Price Target to $15 From $50, Maintains Outperform Rating	MT

07-01	Aptose Biosciences Announces Completion of Acquisition by Hanmi Pharmaceutical	AQ
06-15	Aptose Biosciences : Presents Safety, Response, and MRD Clinical Data from TUSCANY Phase 1/2 Clinical Trial of Tuspetinib Triplet Therapy in Newly Diagnosed AML at the 2026 EHA Congress in Oral Presentation	PU
06-15	Aptose Presents Safety, Response, and MRD Clinical Data from TUSCANY Phase 1/2 Clinical Trial of Tuspetinib Triplet Therapy in Newly Diagnosed AML at the 2026 EHA Congress in Oral Presentation	AQ
05-29	Aptose Biosciences Announces Update on Anticipated Timing of Closing of the Plan of Arrangement with Hanmi Pharmaceutical	AQ
05-13	Aptose Biosciences: Q1 Earnings Snapshot	AQ

12-05	Tokenización: ¿Va a cambiar tanto la vida de los inversores?
12-05	Universo cripto: la tokenizzazione cambierà davvero la vita degli investitori?
09/09/23	Vastzetting: Ethereum scheert hoge toppen - cryptonieuws
08/09/23	Staking: Ethereum raggiunge nuove vette - Resoconto Cripto

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Manager	Title	Age	Since
C. Payne DFI	Director of Finance/CFO	63	26/06/2022
Victor Montalvo-Lugo CTO	Chief Tech/Sci/R&D Officer	-	31/10/2019
Rafael Bejar CTO	Chief Tech/Sci/R&D Officer	54	31/12/2019

Add to a list 0 selected To use this feature you must be a member Log in Sign up	Change	5-day change	1-year change	3-year change	Capi.($)
APTOSE BIOSCIENCES	-7.92%	+21.79%	-	-	4.32M
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ROCHE HOLDING AG	-1.75%	-2.91%	+28.78%	+24.35%	333B
NOVARTIS AG	+0.24%	-2.61%	+29.46%	+46.50%	282B
ASTRAZENECA PLC	-1.75%	-12.77%	+20.67%	+23.05%	267B
NOVO NORDISK A/S	+0.67%	-0.76%	-26.10%	-37.25%	218B
AMGEN INC.	-0.81%	-3.66%	+22.07%	+59.72%	196B
GILEAD SCIENCES, INC.	+1.21%	+0.10%	+19.85%	+72.03%	161B
Average	-0.92%	-3.33%	+26.32%	+55.94%	397.1B
Weighted average by Cap.	+0.02%	-3.10%	+36.27%	+82.99%

	2024	2025
Net sales	-	-
Net income	-25.43M -22.34M -20.71M -19.05M -35.99M -2.43B -36.76M -247M -96.6M -1.19B -95.48M -93.4M -4.13B	-25.47M -22.37M -20.74M -19.08M -36.04M -2.44B -36.81M -247M -96.75M -1.2B -95.63M -93.54M -4.14B
Net Debt	4.49M 3.94M 3.65M 3.36M 6.35M 429M 6.49M 43.58M 17.05M 211M 16.85M 16.48M 729M	26.28M 23.08M 21.4M 19.68M 37.19M 2.51B 37.98M 255M 99.82M 1.23B 98.66M 96.51M 4.27B