John Freund

Medivance, Inc. develops, manufactures and markets therapeutic temperature management products. The company was founded in 1998 and is headquartered in Louisville, CO.

Hansen Medical, Inc. develops, manufactures, and sells medical robotics designed for positioning, manipulation, and stable control of catheters and catheter-based technologies. It offers Sensei Robotic Catheter System which allows physicians to instinctively navigate flexible catheters with stability and control in interventional procedures within the atria heart chambers. The company was founded by Frederic H. Moll, Daniel T. Wallace, Marvin J. Slepian, and Robert G. Younge on November 18, 2002 and is headquartered in Redwood City, CA.

Concert Pharmaceuticals, Inc. is a clinical stage biopharmaceutical company, which discovers and develops novel small molecule drugs through the use of deuterium technology. Its product candidates target a range of diseases including autoimmune disorders, inflammation, and central nervous system disorders. The company was founded by Richard H. Aldrich, Roger D. Tung and Christoph H. Westphal on April 12, 2006 and is headquartered in Lexington, MA.

Acuson Corp. used to design, manufacture and market premium quality medical diagnostic ultrasound imaging systems and image management products. The company was headquartered in Mountain View, CA

Sirtris Pharmaceuticals, Inc., a GSK company, is developing small molecule drugs that target the sirtuins, a family of seven enzymes associated with diseases of aging. Modulation of these enzymes offers the promise of drug discovery in multiple therapeutic areas. Sirtris was one of the pharmaceutical companies focused on the sirtuin platform and remains the innovative drug discovery. Preclinical research indicates that the sirtuins play important roles in pathways for multiple diseases of aging, including Type 2 Diabetes, as well as neurodegenerative, cardiovascular and inflammatory diseases. Sirtris researchers are working to translate this research into a potential new class of pharmaceuticals to treat diseases of aging, offering the ability for people to live longer, healthier lives. Sirtris has focused on developing many novel small molecule activators of SIRT1, the most studied member of the sirtuin family. These new chemical entities or NCEs are novel compounds that are chemically unrelated to resveratrol, a naturally occurring compound that was used as an early proof-of-concept for SIRT1 activation. Besides being structurally differentiated from resveratrol, the NCEs are more specific for the target SIRT1 and have improved drug-like properties. The company has completed several early stage translational clinical studies with the first generation NCEs and has several active clinical trials under way. Sirtris operates as an independent Discovery Performance Unit (DPU) within GSK and is located in Technology Square, Cambridge, Mass. Sirtris' culture mixes scientific curiosity with a dynamic, fast-paced environment, resembling its biotech roots while harnessing all of GSK's broad discovery, development, and commercialization capabilities. The company was founded in 2004 and is headquartered in Cambridge, MA.

Skyline Management LLC (Skyline Management) is a venture capital firm founded in 1997 by John Gordon Freund. The firm is headquartered in Palo Alto, California.

Satiety, Inc. was a medical device manufacturing company. It produced and marketed less invasive devices for the treatment of obesity. The company was founded in 2000 through a collaboration of medical device incubators Thomas Fogarty Engineering and The Foundry and was headquartered in Palo Alto, CA.

Eurofins DiscoverX Corp. develops, manufactures, and commercializes reagents and complete cell-based assay kits and provides profiling and screening services as well as other turnkey solutions for the drug discovery, screening, and life science markets. Its products include cell lines, target engagement assays, biochemical assays, detection reagents, cell culture kits, reagents, and consumables, ligands, and inhibitors, and retroviruses and cloning vectors. The company was founded by Pyare Khanna and Fabrice Plasson in January 2000 and is headquartered in Fremont, CA.

Morgan Stanley Venture Partners (MSVP) is a venture capital firm subsidiary of Morgan Stanley Investment Management Merchant Banking, which is ultimately owned by Morgan Stanley (NYSE: MWD) founded in 1986.The firm is headquartered in New York.

MAKO Surgical Corp. is a medical device company, which develops and markets advanced robotic arm solution, joint specific applications for the knee, hip and orthopedic implants for orthopedic procedures. It also provides RIO robotic arm interactive orthopedic system, including a tactile robotic arm utilizing an integrated bone cutting instrument and a patient specific visualization component. The company was founded by Maurice R. Ferre and Rony A. Abovitz in November 2004 and is headquartered in Fort Lauderdale, FL.

Calypso Medical Technologies, Inc. provided radiation therapy and medical services. The company was founded by Eric R. Meier, Alfred G. Merriweather and Steve Tallman in 1999 and was headquartered in Seattle, WA.

XenoPort, Inc. operated as a biopharmaceutical company. Its products included horizant and regnite. The company was founded by Ronald W. Barrett, William J. Dower and Mark A. Gallop on December 17, 1999 and was headquartered in Atlanta, GA.

Morgan Stanley & Co. LLC is a registered broker-dealer subsidiary of Morgan Stanley Domestic Holdings, Inc., ultimately owned by Morgan Stanley (NYSE: MS) in the US. Headquartered in New York City, the firm was founded in 1987 and provides debt and equity services including underwriting, M&A advice, securities dealing and brokerage and trade execution. Their client base ranges from large global institutional investors to hedge funds at the cutting edge of innovation in the industry.

Crescendo Bioscience, Inc. develops and commercializes quantitative blood tests for rheumatoid arthritis and other autoimmune diseases. It develops quantitative, objective, reproducible blood tests to provide rheumatologists with deeper clinical insight to help enable more effective management of patients with autoimmune and inflammatory diseases. The company was founded by Mike B. Centola and Christopher L. Sutton in July 2002 and is headquartered in South San Francisco, CA.

Advion, Inc. engages in the development, manufacture, and support mass spectrometers, chip-based ion sources, microfluidic flow chemistry systems, and consumables for life science and related industries. Its products include expression CMS (compact mass spectrometer), Plate Express, SOLATION ICP-MS (inductively coupled plasma mass spectrometry), Triversa NanoMate, ASAP (atmospheric esolids analysis probe), and Touch Express. The company was founded by Jack D. Henion and Thomas R. Kurz in 1993 and is headquartered in Ithaca, NY.

Tetraphase Pharmaceuticals, Inc. is engaged in the development and production of novel tetracyclines for serious and life-threatening bacterial infections. It also develops eravacycline, a synthetic fluorocycline, as an intravenous and oral antibiotic for use as a first-line empiric monotherapy for the treatment of resistant and multi-drug-resistant infections. The company was founded on July 7, 2006 and is headquartered in Waltham, MA.

Proteon Therapeutics, Inc. engages in the research and development of biopharmaceutical products. It produces and commercializes vonapanitase for the treatment of renal and vascular disease. The company was founded by F. Nicholas Franano and William P. Whitaker in 2001 and is headquartered in Waltham, MA.

Healthcare Group, founded by John Gordon Freund, is a legal firm that specializes in providing legal advice to medical practices. The firm is based in Plymouth Meeting, PA. The private company offers a range of services including drafting new doctor employment agreements, advising on salary, bonus, benefits, and buy-in provisions, developing buy-in models, creating partnership agreements, advising on corporate counsel, sale or merger, hospital contracts, government regulations and compliance, practice valuation, and retirement plans and employee benefits. The firm has over 40 years of experience in the industry and has helped numerous medical practices with their legal needs.

Arixa Pharmaceuticals, Inc. engages in the development of oral antibiotics for resistant gram-negative infections. The company was founded by Eric Gordon, John Gordon Freund, and Joaquim Trias in 2016 and is headquartered in Palo Alto, CA.

McNally Capital LLC (McNally Capital) is a venture capital firm founded in 2008 by Ward S. McNally and John P. Rompon. The firm is headquartered in Chicago, Illinois.