On April 24, 2018, Kenneth M. Bate notified the Board of Directors of Vanda Pharmaceuticals Inc. that he did not intend to stand for re-election at the company's 2018 Annual Meeting of Stockholders (the Annual Meeting) so that he may devote his full time efforts to his other commitments. The Board will appoint one of the other current directors to succeed Mr. Bate as a member of the Compensation Committee of the Board effective upon the expiration of Mr. Bate's term.