United Therapeutics Corporation announced that Roger Jeffs, Ph.D. has stepped down as the company's President and Co-Chief Executive Officer and David Zaccardelli, Pharm.D. has stepped down as the company's Executive Vice President and Chief Operating Officer. These departures will become effective June 26, 2016. In addition, Dr. Jeffs will not stand for re-election to the company's Board of Directors when his current term expires at the 2016 Annual Meeting of Shareholders, which is to be held on June 21, 2016.

Dr. Jeffs will become a Senior Advisor to the company. Michael Benkowitz, the company's current Executive Vice President, Organizational Development, has been appointed by the Board to become the company's President and Chief Operating Officer, also effective June 26, 2016. Martine Rothblatt, Ph.D., will remain Chairman of the company's Board, and will resume her previous role as sole Chief Executive Officer.