Business description: Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is engaged in discovering, developing, manufacturing and commercializing novel therapeutics based on ribonucleic acid interference (RNAi). Its marketed products include AMVUTTRA (vutrisiran) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR) in adults ; ONPATTRO (patisiran) for the treatment of the polyneuropathy of hATTR amyloidosis in adults; GIVLAARI (givosiran) for the treatment of adults with acute hepatic porphyria; OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1, and Leqvio (inclisiran), which is being developed and commercialized by its partner, Novartis AG, for the treatment of adults with hypercholesterolemia or mixed dyslipidemia. The Company’s clinical development programs include Cemdisiran, Zilebesiran, Elebsiran, Mivelsiran, ALN-6400, and ALN-HTT02. It is developing Cemdisiran to treat complement-mediated diseases.

Number of employees: 2,500

Sales by Activity: Alnylam Pharmaceuticals, Inc.

Fiscal Period: December 2021 (USD) 2022 (USD) 2023 (USD) 2024 (USD) 2025 (USD)

Discovery, Development, Manufacturing and Commercialization of Rnai Therapeutics

844M 1.04B 1.83B 2.25B 3.71B

Geographical breakdown of sales: Alnylam Pharmaceuticals, Inc.

Fiscal Period: December 2021 (USD) 2022 (USD) 2023 (USD) 2024 (USD) 2025 (USD)

United States

325M 473M 689M 934M 2.07B

Europe

260M 315M 399M 516M 651M

Rest of World

77.03M 107M 153M 196M 268M

Executive Committee: Alnylam Pharmaceuticals, Inc.

Manager TitleAgeSince
Chief Executive Officer 63 31/12/2021
Director of Finance/CFO 58 12/08/2019
Chief Tech/Sci/R&D Officer - 31/03/2023
Compliance Officer - 20/09/2022
Chief Tech/Sci/R&D Officer 58 31/08/2016

Composition of the Board of Directors: Alnylam Pharmaceuticals, Inc.

Director TitleAgeSince
Director/Board Member 80 22/04/2012
Chairman 65 04/01/2023
Director/Board Member 72 17/12/2015
Director/Board Member 63 27/10/2021
Director/Board Member 66 31/05/2018
Director/Board Member 70 09/01/2019
Director/Board Member 70 01/03/2020
Director/Board Member 74 21/08/2022
Director/Board Member 69 06/03/2023
Director/Board Member 60 04/01/2026

Shareholders: Alnylam Pharmaceuticals, Inc.

NameStocks%Valuation
Fidelity Management & Research Co. LLC
10.92 %
14,576,437 10.92 % 4 402 M $
Capital Research & Management Co. (World Investors)
8.091 %
10,802,348 8.091 % 3 262 M $
Capital Research & Management Co. (Global Investors)
7.094 %
9,471,181 7.094 % 2 860 M $
BlackRock Advisors LLC
6.26 %
8,357,377 6.26 % 2 524 M $
Vanguard Portfolio Management LLC
4.862 %
6,491,280 4.862 % 1 960 M $

Company details: Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc.

675 West Kendall Street

02142, Cambridge

+617 551 8200

http://www.alnylam.com
address Alnylam Pharmaceuticals, Inc.(ALNY)

Other Pharmaceuticals

Change 5-day change 1-year change 3-year change Capi.($)
+1.89%+4.04%-2.08%+56.00% 39.01B
-0.39%+7.57%+47.95%+156.63% 1,025B
+2.08%+6.33%+52.68%+48.12% 559B
+1.05%+4.65%+19.17%+63.14% 394B
-1.21%+2.94%+18.87%+13.01% 324B
+0.07%+3.42%+50.76%+8.03% 295B
-1.19%+1.47%+26.43%+16.02% 286B
+0.89%+4.76%+21.94%+31.29% 270B
-0.92%-5.41%-45.04%-50.96% 186B
-0.34%+4.97%+18.82%+57.51% 187B
Average +0.19%+3.08%+20.95%+39.88% 356.52B
Weighted average by Cap. +0.15%+4.65%+32.47%+66.01%
Trader
Investor
Global
Quality
ESG MSCI
AA
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
30
Last Close Price
297.69USD
Average target price
445.81USD
Spread / Average Target
+49.76%

Quarterly revenue - Rate of surprise

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