Thermo Fisher Scientific Inc. announced the Thermo Scientific Orbitrap Tribrid Apex and Thermo Scientific Orbitrap Excedion mass spectrometers will be showcased at the American Society for Mass Spectrometry (ASMS) Conference. The Thermo Scientific Orbitrap Tribrid Apex Mass Spectrometer enables researchers to study complex biology across multiomics, structural biology, biopharma characterization and small-molecule analysis on a single system. With five times greater sensitivity, up to 100% sequence coverage in a single experiment and results up to four times faster than previous-generation instruments, the Orbitrap Tribrid Apex allows scientists to better understand challenging samples without requiring multiple systems. Researchers can uncover underlying disease mechanisms earlier and identify therapeutic targets sooner across conditions like cancer and neurodegeneration.

Supporting more than 300 areas of research, the Orbitrap Tribrid Apex MS helps translate these discoveries into faster progress across drug discovery and development. The Thermo Scientific Orbitrap Excedion Mass Spectrometer is designed to help pharmaceutical scientists reduce risk in increasingly complex drug development pipelines. As new modalities such as GLP-1 therapies, oligonucleotides and antibody-drug conjugates introduce greater analytical complexities, identifying and validating key molecular signals early is essential.

With the ability to detect three to five times more compounds in complex samples, the Orbitrap Excedion mass spectrometer provides more complete, regulatory-ready data to support decisions around safety, efficacy and dosing. By enabling earlier detection of low-abundance or previously undetectable molecules, the platform supports earlier identification of critical signals, helping reduce downstream risk, improve regulatory readiness and accelerate time to market. These Orbitrap innovations are part of Thermo Fisher?s broader strategy to connect biological discovery with large-scale validation and real-world research.

At ASMS, the company is also showcasing its Olink proteomics platform, which enables high-specificity protein analysis at population scale and complements Orbitrap-based discovery workflows. Recent software acquisitions, MSAID and Proteinaceous, strengthen Thermo Fisher?s proteomics ecosystem by adding AI, machine learning and proteoform analysis capabilities that help scientists interpret complex population-scale datasets faster and with greater confidence. Instruments are for general lab use only.

Not for diagnostic purposes.