Danish pharmaceutical company Lundbeck is presenting new Phase 1b data for its drug candidate Lu AF28996 at the AD/PD 2026 research conference in Copenhagen.
The study evaluated the safety, tolerability, pharmacokinetics, and early clinical signals in patients with advanced Parkinson's disease.
"Phase 1b patient studies are a crucial step in understanding the safety profile and biological activity of new investigational drugs at an early stage of clinical development," says Johan Luthman, Head of Research and Development at Lundbeck.
"These data provide supporting evidence to further evaluate the potential of Lu AF28996 in treating individuals with advanced Parkinson's disease," he continues.
The results show that the substance was generally well-tolerated and exhibited early signals consistent with its mechanism of action. The company plans to initiate a Phase 2 study in 2026.
H Lundbeck A/S is a Denmark-based company active in the pharmaceuticals industry. It is engaged in the research, development, manufacture and marketing of pharmaceuticals for the treatment of brain disorders, such as Alzheimer’s disease, Bipolar disorder, depression, epilepsy, Huntington’s disease, Parkinson’s disease and schizophrenia. Its product portfolio includes: Cipralex for the treatment of depression and anxiety disorders, Ebixa for the treatment of Alzheimer’s disease, Azilect for the treatment of Parkinson’s disease, Xenazine for the treatment of Huntington’s disease and Sabril for the treatment of epilepsy, among others. The Company operates through a number of subsidiaries, such as Lundbeck SAS, Lundbeck GmbH, SIA Lundbeck Latvia and Lundbeck LLC.
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