Bolt Biotherapeutics, Inc. reported earnings results for the second quarter and six months ended June 30, 2025. For the second quarter, the company reported net loss was USD 8.56 million compared to USD 21.2 million a year ago. Basic loss per share from continuing operations was USD 4.46 compared to USD 11.12 a year ago.
For the six months, net loss was USD 19.6 million compared to USD 32.01 million a year ago. Basic loss per share from continuing operations was USD 10.22 compared to USD 16.8 a year ago.
Bolt Biotherapeutics, Inc. is a clinical-stage biopharmaceutical company developing immunotherapies for the treatment of cancer. The Company’s pipeline includes BDC-3042, an agonist antibody that activates macrophages by targeting dectin-2, and BDC-4182, a next generation Boltbody Immune-Stimulating Antibody Conjugate (ISAC) clinical candidate targeting claudin 18.2. BDC-3042 is in a Phase I dose escalation trial that includes patients with any of seven different solid tumor types. The Company’s Boltbody ISAC platform technology combines tumor-targeting antibodies with immune-stimulating linker-payloads. It has two additional ISAC programs utilizing its Boltbody ISAC technology platform in preclinical development. One is a Boltbody ISAC targeting carcinoembryonic antigen cell adhesion molecule 5 (CEA). Its final Boltbody ISAC program targets PD-L1. The Company is also developing additional Boltbody ISACs in strategic collaborations with biopharmaceutical companies.
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